Computer-Aided Identification of Bioactive Compounds of Azadirachta Indica (Neem) with Potential Activity against SARS-CoV-2 Main Protease

Titilayo O Johnson*; Abayomi E Adegboyega; Olugbenga E Adeyemi; Francis O Okonkwo; Stephen A Ejembi; Jane-Rose I Oche; Emmanuel A Oluwarotimi; Farida Bashar; Grace Inioluwa Johnson; Oluyomi Stephen Adeyemi

oronavirus disease 2019 (COVID-19) is a zoonotic disease caused by a novel virulent virus known as Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Up till now, there is a continuous increase in cases, morbidity and fatality associated with the disease throughout the world. Azadirachta indica (Neem) is a medicinal plant popularly known for its antimalarial and broad-spectrum antiviral activities...