IMPACT FACTOR: 1.4
Targeted Osmotic Lysis (TOL) has been recently proposed as a novel, safe, and effective method for treating advanced carcinomas. The technique takes advantage of the finding that carcinomas greatly over-express Voltage-Gated Sodium Channels (VGSCs)
Malignant melanomas are often misdiagnosed or discounted when the disease is present in early, more treatable stages. When present during later stages of disease treatment options tend to be more limited, less effective, and prone to association with significant adverse effects.
Blood is a red, dark and thick fluid, with a salty taste and particular scent, that streams through the blood vessels and the heart. It passes through all parts of the body, supplies it with supplements and oxygen, and carries destructive substances to the organs that discharge or neutralize them.
Juvenile granulosa cell tumor is a sex cordstromal tumor, which is the leading cause of precocious puberty. Massive hemorrhagic ascites at early stage was rarely reported. Here we report a rare case of Stage 1A juvenile granulosa cell tumor with massive hemorrhagic ascites in a 5 years old Eritrean child.
Melanoma has the highest prevalence of somatic mutations among all malignancies [1-5]. Primary lung melanoma is rare, representing 0.01% of all primary lung tumors [6-11]. We present a case with no common melanoma-associated mutations but a mutation in the ARID1A K1010R gene, highlighting a novel mutation that may guide future research and therapies.
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