Short Name: Chronicles Oncol
ISSN: 2638-4248
Publisher: MedDocs Publishers LLC
A 35-year-old male presented with acute abdomen with intra-abdominal hemorrhage. He had bilateral cryptorchidism and infertility. Immediate laparotomy was carried out. Excision of the tumor, right hemi colectomy and peritoneal toilet was done...
Among the various forms of cancer is penile cancer, considered as a rare neoplasm and affects 1/100,000 men in developed countries. In Brazil, these tumors correspond to 2% of malignant neoplasms in men, being five times more prevalent in the North and Northeast regions compared to other regions. Aiming to write the incidence of penile cancer in the state of Espírito Santo (ES) in the period 2000-2018.
Squamous Cell Carcinoma (SCC) is a type of cancer, in which, mainly, skin, mouth and esophagus are pronto being affected. As a specified type of this carcinoma, Cutaneous Squamous Cell Carcinoma (CSCC) is regarded as the second most common non-melanoma skin cancer. About 250,000 cases of CSCC, are diagnosed annually, meanwhile, statistics depict a dramatic upsurge that culminated to 5 million in 2011. Classical risk factors of CSCC comprising age, ethnicity, skin phototype, Ultraviolet (UV) exposure, and immunocompromised.
Chemoresistance in cancer therapeutics is an emerging problem and led to relapse and poor prognosis. Development, progression, and metastasis of tumor is regulated by signaling pathways including PI3K, Akt, mTOR, NF-κB, ERK, MAPK, MEK, JAK/STAT, mTOR, HER-2, and EGFR signaling pathways. However, aberrant expression of these pathways as well as of epigenetic regulation including methylation, acetylation, microRNAs, and lncRNAs imparts chemo resistance in cancer...
Although all the thyroid carcinoma are rare in young adults but the Thyroid follicular carcinoma is the rarest one. Almost 90% of thyroid carcinomas are papillary while 6% of them are the follicular. The incidence of carcinoma thyroid in people in their twenties or younger age is absolutely rare i.e. 1 in million in world wide. The case I am presenting is a juvenile thyroid follicular carcinoma showing rapid growth of a goiter.
Vitamin E is a group of antioxidant to copherols and to cotrienols that have been shown to have a potential role in chemoprophylaxis. However, whether vitamin E can reduce the risk of prostate cancer remains controversial.
Melanoma, known for its aggressive progression and metastatic potential, remains a significant therapeutic challenge. This study aimed to investigate the anti-cancer effects of human IFN-ɛ, a neotype I interferon with potential tumor-inhibiting and immune-modulating properties, on melanoma cells.
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