IMPACT FACTOR: 1.8
Short Name: J Nanomed
ISSN: 2578-8760
Publisher: MedDocs Publishers LLC
PEGylation first discovered for proteins to avoid immune response, has been widely recognized as a gold standard for lipid nanoparticles to prevent aggregation and reduce opsonization by blood proteins, and to avoid clearance by macrophages to help extend the longer systemic circulation ...
Despite advancements in screening, diagnosis, and treatment approaches, Colorectal Cancer (CRC) is one of the most common cancers diagnosed globally and continues to be a major cause of cancer-related mortality, contributing significantly to the global disease burden [1-3]. Due to aggressive ...
Spray drying technology has been used extensively for converting highly crystalline and high melting molecules to Amorphous Solid Dispersions (ASD) to overcome the solubility and bioavailability challenges [1].
Zinc oxide nanoparticles (ZnO-NPs) are being widely studied for biological applications due to their adjustable physicochemical characteristics and possible antibacterial and anticancer effects. However, variable toxicity results and unsolved biosafety issues preclude their clinical use.
Proteolysis Targeting Chimeras (PROTACs) discovered over 20 years ago, have been classified as molecules beyond rule of five (bRoF), meaning they do not follow the classic Lipinski’s rule of five for solubility and bioavailability [1].
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