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Down syndrome and incidental pediatric basal ganglia calcifications at autopsy

Richard A Prayson

    Basal ganglia calcifications in the pediatric population are an unusual finding and in radiologic studies, have been noted in between 1-2% of patients in that age group. The causes for calcification are myriad but most commonly include tumors, congenital infections and tuberous sclerosis. The current report describes a case of a 17-year-old female with Down syndrome (trisomy 21) who presented with agitation, dry cough, decreased appetite, and fever. She experienced a 3 minute apneic episode followed by cardiopulmonary resuscitation...


Possible prevention of postoperative nausea and vomiting

Simon B N Thompson

    Postoperative Nausea and Vomiting (PONV) are frequently reported. Prominence following cardiac surgery and particularly associated with pediatric adnexal surgery in non-menstruating females is less well documented but nonetheless anecdotally known to anesthetists and adnexal surgeons. Risk of PONV, based on four independent risk predictors, may be assessed using scoring systems such as Apfel; however, Apfel is dependent upon age and guidelines are available for adults undergoing surgery...


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