Archive

Conjunctival Lymphoma Revealing a Small Cell Lymphoma

Lazaar Hamza*; Meryem Sefrioui; Taha Boutaj; Najoua El-Moubarik; Boutayna Azarkan; Noureddine Boutimzine

    We report the case of a 52 -year-old male patient with no particular previous history, presenting to the emergency ophthalmology with Unilateral conjunctival mass in the right eyes that had progressively increased over the last two months.


The Potentiation Effect of Grasping Behaviors: Coding and Simulation Processes Operating Simultaneously

Mohamed Halim Harrak*; Loïc P Heurley; Vincent Dru

    The motor potentiation effect of grasping behaviors, namely the fact that the mere perception of agrasping object facilitates compatible motor response. According to the simulationnist account [1], ata conceptual level, there would be an involvement of motor processes, which will produce motor simulation.


Intraocular Fluid Sampling In Patients with Sight Threatening COVID-19 Ophthalmic Sequelae

Srinivasan Sanjay*; Venkata Ramana Anandula; Padmamalini Mahendradas; Chaitra Jayadev; Ankush Kawali; Rohit Shetty

    Background: Coronavirus disease 19 (COVID-19) has been associated ophthalmic sequelae following recovery. Purpose: This study explores the possible role of the severe acute respiratory syndrome corona virus (SARS-CoV-2) in ophthalmic manifestations by analyzing the ocular samples.


Unilateral Florid Proliferative Radiation Retinopathy in Orbital DLBCL

Rahul P Vijaykumar; Nawazish Shaikh*; Rohan Chawla

    A 35-year-old male presented with complaints of diminu tion of vision and floaters in OS for 2 months. Best corrected visual acuity was 20/20 and 20/80 in OD and OS respectively.


Exploring the Potential of ChatGPT for Advancing Oculoplastic Surgical Research

Ishith Seth*; Gabriella Bulloch; Yi Xie; Zhuoting Zhu

    ChatGPT, an open-source Artificial Intelligence (AI) chatbot, utilizes deep learning to generate human-like textual dialogues. Its potential applications within the scientific community are extensive, yet its effectiveness in providing innovative ideas on various topics remains unexplored.


Artificial Intelligence Applications and Performance Metrics in Ophthalmology: A Systematic Review and Meta-Analysis

Gabriella Bulloch; Ishith Seth*; Zhuoting Zhu; Fiona Jane Stapleton; Adrian Fung; Zachary Tan; Hugh R Taylor

    To evaluate the overall performance of various Artificial Intelligence (AI) models in ophthalmology for the diagnosis of various ophthalmic diseases despite of variations in methodology, platforms built, and workflows. AI technologies can revolutionize ophthalmology and vision sciences through automating image analysis.


Posterior Lenticonus Revealed by Congenital Cataract

Meryem Sefrioui*; Saoiabi Yahya; Hamza Lazaar; Salma Hamidi; Narjisse Taouri; Lalla Ouafa Cherkaoui

    We report the case of a 4-year-old, only child in his family, with no personal or family history. He consulted for a leukocoria of the left eye never explored before. Ophthalmologic examination of the left eye revealed visual acuity reduced to light perception.


Acute Submacular Haemorrhage Secondary to Wet AMD

Mohanad Moustafa

    This is a wide field fundus photograph of the right eye of an 83-year-old patient with wet AMD. The image shows extensive sub retinal haemorrhage involving the macula and extending superiorly and inferiorly with serous retinal detachment inferiorly as a complication of wet AMD. Best corrected visual acuity dropped from 6/9 to HM. The patient underwent Intravitreal injection of Tissue plasminogen activator (tPA), Anti-VEGF and gas to displace the blood from the macula.


Smartphone Technique for Fundoscopy, Step by Step

Robinson Barrientos; Fernando Godin; Eduardo Cadena; Ana Luisa Gonzalez MD; Maria Adelaida Piedrahita*; Maria Andrea Estevez-Florez

    To describe a relatively simple technique for fundus photography in humans using a smartphone and an indirect ophthalmoscopy lens. Fundus images were captured using smartphones (iPhone and android) and a 2.2 mm, 20 D, or 28D Pan retinal® lens. Using the phone’s light source, this system functions as an indirect ophthalmoscope that creates a digital image of the fundus.


The Secretome of Stem Cell from Apical Papilla Improves Hydrogen Peroxide Induced Retinal Toxicity in Rat, an Animal Study

Alireza Dehghani*; Mohammad Malekahmadi; Fereshteh Karamali; Sareh Soroushzadeh; Heshmatollah Ghanbari; Ardeshir Talebi; Mohammad Hossein Nasr Esfahani*

    Retinal damage can lead to severe and permanent visual loss. Mesenchymal stem cell and their secretome containing stem cell-derived factors and have been shown to have proliferative and anti-inflammatory properties. Therefore, the aim of this study was to assay the conditioned medium derived from the stem cells from apical papilla (SCAP) on retinal toxicity induced by H2O2 in rats.


Beyond the Canaliculus… Umbrella Induced Pediatric Trauma. A Case Report

Aoife Naughton*; Jennifer Doyle; Louise Acton; Richard Scawn

    A 6-year old boy was referred to the oculoplastic team for repair of a left upper lid laceration involving the superior canaliculus. He had presented to the eye casualty following a fall at home onto the plastic tip of a child size umbrella, which was un-witnessed. On examination, he was alert and oriented with a GCS of 15. There was a 1cm partial thickness oblique laceration of the left upper eyelid extending into the medial canthus, transecting the superior canaliculus.


Ocular Metastasis in Pancreatic Cancer: Prevalence and Literature Review

Hana A Mansour*; Walid Faraj*; Mohamad J Khalife; Mariam Kanso; Ali Shamseddine; Deborah Mukherji; Ahmad MMansour

    Purpose: To assess the prevalence of ocular metastasis in pancreatic cancer (PC) as little is known in the literature.
Methods: Prospective cross-sectional study of consecutive patients with PC at the time of initial diagnosis in one medical center. Complete eye exam was performed by a single operator. A literature review was done to collect cases of metastatic eye disease in PC.


Orbital Ultrasonography for Measuring Meaningful Orbital Inflammatory Responses

Hadi Khazaei*; Danesh Khazaei; Davin Ashraf; Shravani Mikkilineni; John D Ng

    Ultrasound being a portable imaging device that is capable of making fast regional estimates of body composition, is an attractive assessment tool in instances when other methods are limited (risks of contrast in MRI and or radiation in CT scan). Furthermore, much of the research suggests that it is reliable, reproducible, not only an accurate means of diagnosing Thyroid Associated Orbitopathy (TAO) pathology and predicting its clinical course, but as a way to follow the course of the disease and the response to treatment as well...


Ultrasonographic Characteristics of the Facial Nerve in Patient with Bell’s Palsy

Hadi Khazaei*; Danesh Khazaei; Davin Ashraf; Shravani Mikkilineni; John D Ng

    Peripheral facial paralysis is a diagnostic challenge. Acute facial palsies are mostly “idiopathic” (Bell’s palsy) but it is a diagnosis of exclusion, and therefore cases of acute, acquired, isolated peripheral facial paralysis should be investigated thoroughly. Comprehensive efforts should be made to diagnose the cause, because some percentages of the patients referred with a diagnosis of Bell’s palsy were found to have a treatable, progressive, or life-threatening lesion.


Overview of Orbital Ultrasonography

Hadi Khazaei; Danesh Khazaei; Davin Ashraf; Shravani Mikkilineni; John D Ng

    Ultrasonography contains a wide selection of clinical indications. For instance, when examining a patient with ocular discomfort or pain, clinicians will use ultrasound to ensure a diagnosis of inflammation, orbital myositis, or dacryoadenitis. Imaging is often used to identify retrobulbar tissue, as well as the extraocular muscles, in patients with symptoms and suspected soft tissue enlargement secondary to Graves’ disease.


A Bibliographic Study and Quantitative Analysis of Age-related Macular Degeneration and Fundus Images

Han Wang*

    Age-related Macular Degeneration (AMD) is regarded as one of the main causes of irreversible vision loss in the elder. The increasing number of AMD patients is expected to reach 288 million by 2040. Detecting methods based on fundus images have become the main diagnostic approach for AMD. Therefore, this paper makes a systematic review analysis of AMD diagnosis based on fundus images. Methodologies of bibliography and text mining are included...


Retardation of Myopic Progression and Axial Growth in Children by Atropine

Mitsugu Shimmyo*

    Purpose: To determine the effect of atropine on axial length elongation by prospectively examining axial lengths and parameters of refraction in atropine treated and untreated eyes of myopic children.
Design: Randomized prospective clinical trial.
Methods: Four hundred and ninety-two myopic children participated in this study. (Mean age 10.1 years, ranging 5 and 16 years) Initial examination for both treated and control groups included cycloplegic refraction (initial refraction between -0.50 and -3.50D), tonometry, keratometry and axial length measurement by A-scan ultrasonography...


Fresh Amniotic Membrane Transplantation in Ocular Surface Disorder in a Tertiary Teaching Care Hospital, Eastern India

Suchismita Mishra; Swati Samant*; Ramesh Chandra Mohapatra; Bhabani Shankar Pati; Srikant Kumar Dhar; Chinthala Navyasree

    Aim: Evaluating the efficacy of fresh Human Amniotic Membrane (HAM) for various ocular surface reconstructions.
Materials and methods: 54 eyes of 50 patients having ocular surface disorders were evaluated. Out of which 31 patients were male and 19 were females. Indications for AMT included pterygium (18 eyes), bullous keratopathy (4 eyes), climatic droplet keratopathy (3 eyes), Steven Johnson syndrome (14 eyes), chemical burn (3 eyes), corneal ulcer (7 eyes), band keratopathy (2 eyes) and shield ulcers (2 eyes). Fresh amniotic membrane was used in all the cases...


The 'Om' Sign

Anubhav Chauhan*; Deepak Sharma

    A 65-year-old male came to our OPD for routine eye checkup. He had no ocular complaints. His history was uneventful. On examination, his best-corrected visual aquity was 6/6 in both the eye. Ocular movements, pupillary reaction, intraocular pressure and Colour vision were normal. Examination of the fundus of the left eye was within normal limits with a cup disc ratio of 0.3 while the right optic disc had a cup disc ratio of 0.7...


Ocular Chemical Burn Due to an Intentional Self-Administration of Bitter Melon Juice to Ocular Surface and Mini-Review of the Literature about the Traditional Eye Medication Related Ocular Burns

Ilayda Korkmaz; Seray Sahin; Ozlem Barut Selver*

    Purpose: To report a case of ocular chemical burn caused by intentional topical self-administration of bitter melon (Momordica charantia) juice to treat presbyopia symptoms.
Methods: This is a case report and brief review of related literature
Results: A 45-year-old male presented with irritation, pain and discharge in the right eye after an intentional instillation of bitter melon juice in order to treat his new-onset of presbyopia symptoms. Best corrected visual acuity (BCVA) was 20/100 OD...


Evaluation of Corneal Endothelial Cell Loss Peak in Young Healthy Turkish Population

Onur Furundaoturan; Ozlem Barut Selver*; Melis Palamar

    Clinical relevance: It is significant to determine main endothelial cell loss peak decades in order to decide surgical intervention time and be prepared for vital precautions in patients requiring ocular surgery.
Background: Although, endothelial cell loss during natural course of aging is an obvious clinical manifestation, remarkably in some ethnicities such as Turkish population, younger decades tend to have one of the main loss peaks...


A Bilateral Christmas tree Cataract Case

Sima Sheikhghomi

    This photograps belongs to a 75-year-old diabetic woman who presented to our clinic with bilateral progressive decreasing vision from a few years ago. She had a best-corrected visual acuity of count finger at 2 ms in her right eye and 20/200 in the left one by the Snellen chart. On the slit lamp examination, multiple clusters of poly chromatic and highly reflective needle-like crystals were seen within the cortex of the lenses of both eyes. In this case, the patient also had a Moderate to severe non-proliferative diabetic retinopathy and macular ischemia in her both eyes, which was the main cause of reduction of her vision.


3-Year Outcomes of Excisional Goniotomy with the Kahook Dual Blade for Glaucoma in Bolivia

Manuel Jose Justiniano*

    Purpose: To characterize long-term Intraocular Pressure (IOP) and IOP-lowering medication reductions through 3 years following Excisional Goniotomy (EG) using the Kahook Dual Blade (New World Medical) combined with phacoemulsification in Bolivia.
Methods: This was a single-surgeon, retrospective analysis. Preoperative and postoperative IOP and medication use data were collected through 3 years of follow-up. Changes from baseline were analyzed using paired t-tests.


Intrapapillary Hemorrhage with Adjacent Peripapillary Subretinal Hemorrhage in Myopic Chinese Adolescents

Julia YY Chan*; Carmen KM Chan; Jerry KH Lok; Noel CY Chan

    Background: To report three cases of Intrapapillary Hemorrhage with Adjacent Peripapillary Subretinal Hemorrhage (IHAPSH) in Chinese adolescents, and to review the published literature on IHAPSH.
Case presentation: Three patients were diagnosed with IHAPSH in a tertiary ophthalmic centre in Hong Kong between 2007 and 2019. All patients were young Chinese with moderate to severe myopia, and crowded/tilted discs, presenting with unilateral optic disc hemorrhage...


Clinical Practice beyond Covid-19 Pandemic: Preparing for an Uncertain Future

Aatish Saraswat; Ankita Singh*

    The ongoing COVID-19 pandemic plaguing countries worldwide has created an unprecedented change for the global economy, especially healthcare institutions at the forefront. Acceleration of the online-offline integration is the need of the hour. Massive expansion of home-based care likely will be supplemented with Artificial Intelligence (AI). One particular sector that has the greatest potential to benefit from tele-health services is the rural sector across all countries...


SARS-CoV-2: An Ophthalmological Insight into the Pandemic; Challenges and Management Strategies

Jaya Kaushik; Sandeep Shankar; Anargh V; Renu M*; Ankita Singh; Rakesh Shetty

    Objective: To formulate a protocol for safe and effective management of an ophthalmologic practice in a hospital or a clinic during the Covid - 19 pandemic.
Methods and analysis: Literature was reviewed regarding Covid-19 pandemic and ophthalmology. The following key words were used. Covid-19, telemedicine, challenges, management strategy.


Results of Selective Laser Trabeculoplasty (SLT) in lowering intraocular pressures (IOP) at 6 weeks

Yew Chong Yap*; Laura Boddy; Siddharth Agrawal

    Background: Various treatments modalities have been advocated to treat patients with glaucoma or OHT. Selective Laser Trabeculoplasty (SLT) has been highlighted recently for treatment of glaucoma patients.
Objectives: To analyse the reduction of IOP with SLT treatment.
Design: A retrospective study on 24 eyes treated with SLT treatment.


Impact of COVID-19: Identifying the Barriers in Ophthalmology Training

Jaya Kaushik*; Eram Riyaz; JKS Parihar; YVK Chaitanya; Ankita Singh; Rakesh Shetty

    Introduction: Actions taken to carry out sustainable practice in ophthalmology during the COVID-19 pandemic have put the training process at an impasse. There is an enormous reduction in surgical volume and patient care by residents.
In this article the authors discuss the primary challenges faced by ophthalmology residents during the pandemic and propose potential solutions.


Comparisons between Kahook Dualblade (KDB) Goniotomy vs Selective Laser Trabeculoplasty (SLT)

YC Yap*; Laura Boddy; Siddharth Agrawal

    Participants: POAG or OHT patients in one or both eyes who were aged ≥ 18 years, able to provide informed consent, visual acuity of at least 6/36 in the study eye with suboptimal IOP control despite on antiglaucoma medications. Patients were excluded if they had congenital, early childhood or secondary glaucoma or ocular comorbidities, if they had any previous ocular surgery except phacoemulsification. Patients in the SLT group should not have previous SLT treatment before.


Imaging of High - or Low-Abundance Proteins on the Rod Outer Segment Disks

Daniela Calzia; Paolo Bianchini; Federico Caicci; Lucia Manni; Silvia Ravera; Carlo Enrico Traverso; Alberto Diaspro; Isabella Panfoli*

    Our previous proteomic and biochemical studies suggest that the respiratory chain complexes I to V are expressed in the rod Outer Segment (OS), an organelle devoid of mitochondria, specialized for visual transduction. The expression of the cited proteins was demonstrated with several imaging techniques, even though co-localization only proved significant on retinal sections.


Mowat-Wilson Syndrome

Bogumila Wojcik-Niklewska*; Monika Sarnat-Kucharczyk; Erita Filipek

    Introduction: Mowat-Wilson syndrome is a rare genetic condition resulting in multiple congenital anomalies including facial dysmorphism, structural anomalies of the internal organs, functional disorders and, although less commonly, ocular abnormalities.
Aim: To present a child with Mowat-Wilson Syndrome and eye abnormalities.


Ophthalmological Examination of Newborns with Hypoxic-Ischemic Encephalopathy Treated with Therapeutic Hypothermia

Bogumila Wojcik-Niklewska*; Monika Sarnat-Kucharczyk; Erita Filipek; Jerzy Sobczyk; Janina Kohut

    Background: The aim of the study was to evaluate the visual organ in children with severe hypoxic-ischemic encephalopathy treated with controlled hypothermia.
Methods: Controlled hypothermia was performed in the Neonatal Intensive Care Unit in Zabrze using the CritiCool & Cure Wrap System. Children were qualified and examined by neonatologists. All children were treated with whole-body hypothermia for 72 hours with a target temperature of 33 to 34°C in analgosedation with through biophysical monitoring.


Valsalva Retinopathy After Sports Exercises: Case Report at Iota Teaching Hospital

Elien Gangnan Yan zaou tou Rodrigue Romuald*; Bakayoko Seydou; Sidibe Mohamed Kolé

    Purpose: Report a case of Valsalva retinopathy that occurred during sport by analysing its clinical and therapeutic specificities.
Methodology: This is the report of a clinical case received in consultation on Monday 21st December 2020 at the ophthalmological investigation department of the IOTA-Teaching Hospital.


Refractive Red Reflex Test in Zonular Cataract

Amber Amar Bhayana*; Priyanka Prasad; Sudarshan Kumar Khokhar

    Here Hypermetropia in a 4 year old with zonular cataract (Figure 1a) is demonstrated with red reflex with indirect ophthalmoscopy as a bright area is seen in inferior part of the eye (Figure 1b) [1,2,3]. It is hard to pick up the same sign using red reflex with direct ophthalmoscope (Figure 1c) due to lesser distance between illumination and visualization axes in direct ophthalmoscope (as compared to indirect) allowing formation of better crescent that too just only through a peripheral rim...


Relationship between OSDI, Tear Break Up Time, Schirmer Test and Pterygium Grades in Pterygium Patients

Onur Gokmen*; Ipek Genc

    Aim: To investigate the relationship between OSDI (Ocular Surface Disease Index), the Schirmer test, and tear Break Up Time (BUT) measurements in patients with pterygium and compare this according to pterygium grades. Methods: The BUT measurements and the Schirmer tests were evaluated in patients with pterygium, and OSDI questionnaires were applied. OSDI scores were calculated, and the patients were grouped according to their OSDI scores.


Crystals in the Eye

Vinit Shah*; Syed Mohideen Abdul Khadar; Shobita Nair

    A 48 years old female presented to us with defective vision in both the eyes since 1 year. Her BCVA in RE was 6/18 and in LE 6/9. Both eyes anterior segment examination was within normal limits and posterior segment showed glistening, yellow-white intraretinal crystals in the posterior pole, atrophy of the retinal pigment epithelium & choroidal sclerosis.


A Pictorial Study of How Spherical Aberration Affects Image Quality after LASIK

Raphael L Vazquez

    Spherical aberrations are known to increase after LASIK surgery. This can cause problems with the vision at night when the pupil size increases to adjust for the darkness. The purpose of this paper is to show through photographs how spherical aberrations affect image quality.


The eye protection factor (EPF®): An improved solar UV rating system for sunglasses

Gary W Hall

    Background/aims: Serious eye diseases caused from exposure to solar radiation continue to be a global public health hazard. Within the electromagnetic spectrum, the ultraviolet (UV) band and some of visible light band (high energy visible (HEV) light) pose the greatest health hazard to the human eye from solar radiation exposure. Wearing appropriate sunglasses is the most practical and cost-effective way of protecting the human eye from harmful solar radiation...


Clinical retrospective analysis of hospitalized patients with ocular trauma

Liang Liang*; Li Qin-Hua; Liang Li-Cheng

    Objective: To analyze the related factors of ocular trauma in ophthalmic inpatients and provide epidemiological data on local ocular trauma. Methods: 1137 cases of 1610 eyes with ocular trauma admitted to our hospital from January 2014 to December 2018 were selected for statistical analysis of general conditions, causes of injury, prognosis and complications.


NO news is good news for eyes: A mini review

Mir JM*; Maurya RC*

    Nitric Oxide (NO) is a well known endogenous gasotransmitter with profound effects on mammalian physiology and also possesses major therapeutic implications. Despite the known toxicity of this molecule when present above the optimal concentration, plays key signaling and regulatory role in human life processes. From the literature survey it is evident that NO bears potential role almost in every system of human body. Among these systems nervous system has also been found linked with this molecule.


Radiation damaging effects on ocular tissues

Yuan-Hao Lee*; Randolph D Glickman

    The human eye, composed of specialized tissues, has unique functions to admit or receive certain wavelengths of electromagnetic radiation. In order to integrate information from the entire visual field, visible light is collected and focused by the spherical lens onto retinal neurons. Excessive light exposure, however, not only mediates photoreceptor activation but also induces photodamage effects.


Management of post operative seclusio pupil and corneal decompensation

Arjun Srirampur, MS, FRCS*; Kavya Reddy, MS; Aruna Kumari Gadde, MS; Sunny Manwani, DNB

    A 71 year old man presented with a history of cataract surgery in both eyes and gradual diminution of vision post surgery in right eye (RE) since 3 years. On examination RE showed corneal decompensation with seclusio pupillae with a small pupil and a posterior chamber intraocular lens (PCIOL). He was diagnosed with pseudophakic bullous keratopathy (PBK). He underwent DSAEK (Descemet's stripping automated endothelial keratoplasty ) with synechiolysis and pupilloplasty. Graft lenticule was well attached to the host tissue with a vertically oval pupil and subsequent improvement of vision.


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